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The Lepto Vaccine

Read all of the articles in our Vaccines & Titers intro series here:

  1. Vaccination Schedules

  2. Considering “Non-Core” Vaccines

  3. A Look at Titer Testing

  4. The Lepto Vaccine

  5. Vaccine Reaction Resources

You can also visit our Vaccines & Titers topic page for a look at all of the articles in this category.


Unless your puppy is considered high risk for leptospirosis, we recommend against vaccinating for lepto.


Problems Associated with the Lepto Vaccine

“There’s still a fairly high percentage of dogs that do not respond to the 4-way vaccine. In addition, of all the bacterin vaccines, leptospirosis causes the most adverse reactions.” Dr. Ron Schultz, Chair of the Department of Pathobiological Sciences at the University of Wisconsin School of Veterinary Medicine

Resources for High Risk Dogs who Need the Lepto Vaccine


Dr. Ron Schultz Update on Leptospirosis Vaccines Describes the proper schedule for vaccinating against lepto, and which strains to include.


Leptospirosis in Dogs Covers the symptoms, diagnosis, treatment, and prevalence/communicability of lepto. Contains additional references.


Snapshot of Leptospirosis Strains and Vaccine

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